Nitric oxide, ischaemia and brain inflammation.

نویسندگان

  • S Murphy
  • C L Gibson
چکیده

Cerebral ischaemia results in the activation of three isoforms of NOS (nitric oxide synthase) that contribute to the development of and recovery from stroke pathology. This review discusses, in particular, the role of the transcriptionally activated NOS-2 (inducible NOS) isoform and summarizes the outcomes of experimental stroke studies with regard to the therapeutic utility of nitric oxide donors and NOS inhibitors.

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 35 Pt 5  شماره 

صفحات  -

تاریخ انتشار 2007